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Viagra (Sildenafil) + Lisinopril
Can you take these together?

🇺🇸 Based on FDA Data · Free
✅
No Known Interaction
Viagra (Sildenafil) + Lisinopril

No drug interaction found in current databases. Always consult your pharmacist or doctor before taking medications together.

📊 Data Sources
🇺🇸FDA openFDA API — Drug interaction data sourced from the U.S. Food & Drug Administration's official drug label database (openFDA). The same data used by U.S. healthcare professionals. FDA official site →
🇰🇷MFDS DUR API (Korea) — Contraindication data from South Korea's Ministry of Food and Drug Safety (MFDS) Drug Utilization Review public API. Covers 44,000+ medications. MFDS official site →

⚕️ This information is for reference only and does not constitute medical advice. Always consult a doctor or pharmacist before taking medications.

🔍 Check Another Combination
💊 Drug Information
MedicationViagra
Always consult your doctor or pharmacist about Viagra interactions before combining with other medications.
ACE Inhibitor / Blood PressureLisinopril(Lisinopril)

Lisinopril is an ACE (angiotensin-converting enzyme) inhibitor used to treat high blood pressure, heart failure, and to protect the kidneys in diabetic patients.

🔬 How It Works

By inhibiting ACE, lisinopril prevents conversion of angiotensin I to angiotensin II (a potent vasoconstrictor), resulting in vasodilation, reduced aldosterone secretion, and lower blood pressure.

💡 Common Uses
  • High blood pressure (hypertension)
  • Heart failure management
  • Post-heart attack heart protection
  • Diabetic nephropathy (kidney protection)
  • Chronic kidney disease
⚡ Side Effects
  • Dry persistent cough (very common, ~10–15% of patients)
  • Dizziness, especially on standing (orthostatic hypotension)
  • Elevated potassium (hyperkalemia)
  • Rare but serious: angioedema (swelling of face/throat)
  • Kidney function changes
⚠ Caution: Avoid in pregnancy (teratogenic). Monitor potassium and kidney function. NSAIDs reduce effectiveness. Report angioedema immediately.

💊 Drug Interaction Safety Guide

What is a Drug Interaction?

A drug interaction occurs when one medication affects the activity of another when taken simultaneously. This can increase or decrease the effectiveness of a drug, or cause unexpected side effects. Over-the-counter medications, supplements, and even foods can also interact with prescription drugs.

3 Types of Drug Interactions

  • Pharmacodynamic — Two drugs act on the same receptor, amplifying or canceling each other's effects
  • Pharmacokinetic — One drug affects the absorption, distribution, metabolism, or excretion of another (CYP450 enzyme interactions are common)
  • Physicochemical — Drugs bind together, reducing efficacy or forming toxic compounds

Seek Immediate Medical Attention If You Experience:

Difficulty breathing or chest painSevere dizziness or faintingUnusual bleeding or bruisingSevere nausea, vomiting, or stomach painJaundice (yellowing of skin or eyes)Severe hives or swellingSudden muscle pain or weaknessConfusion or loss of consciousness

Food & Drug Interactions

  • Grapefruit — Inhibits CYP3A4 enzymes, raising blood levels of statins, calcium channel blockers, and immunosuppressants
  • Alcohol — Interacts with most drugs including sedatives, pain relievers, and blood thinners; increases liver burden
  • Dairy & Calcium — Impairs absorption of tetracyclines, quinolone antibiotics, and thyroid medications
  • Vitamin K-rich foods (leafy greens) — Weakens warfarin's blood-thinning effect; maintain consistent daily intake

Before Taking Any Medication

  • Tell your doctor or pharmacist about all medications you take (prescription, OTC, supplements, herbal products)
  • Disclose if you are pregnant or planning to become pregnant
  • Take medications with water — avoid juice, milk, or alcohol
  • Follow dosage instructions carefully — never double a missed dose
  • Complete the full course of antibiotics even if symptoms improve
This guide provides general educational information and does not constitute medical advice. For personalized medication guidance, consult your doctor or pharmacist.
Frequently Checked Combinations
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